Excessive alcohol use can harm the body in many ways, including an increase in the risk of various cancers. It damages liver cells, leading to inflammation, scarring and serious conditions such as cirrhosis. Dr. Andrew Keaveny, a Mayo Clinic transplant hepatologist, says heavy drinking also can lead to alcoholic hepatitis, which is becoming more common in younger […]
Mayo Clinic surgeons have found that an innovative approach can help patients with obesity get lifesaving care. Obesity can be a barrier to liver transplant. Dr. Julie Heimbach, director of the Mayo Clinic Transplant Center in Rochester, Minnesota, says that combining gastric sleeve surgery, a type of bariatric surgery with liver transplantation is effective in addressing both health issues. […]
RESEARCH BRIEFINGS 01 January 2025 Metabolic-dysfunction-associated steatohepatitis (MASH) is defined by lipid accumulation and inflammation, and makes liver cells enter a tumour-suppressive state called senescence while increasing cancer risk. Investigation of this paradox reveals that MASH-inducing diets trigger senescence by causing DNA damage. However, prolonged metabolic stress allows once-senescent liver cells to start dividing and […]
Liver cancer rates have more than tripled in the U.S. since 1980 and continue to rise. More than 41,000 people will be diagnosed with liver cancer in the U.S. this year, and about 29,000 will die from the disease, according to the American Cancer Society. Dr. Lionel Kankeu Fonkoua, a Mayo Clinic Comprehensive Cancer Center […]
Nature, Published online: 04 December 2024; doi:10.1038/d41586-024-03653-2 Fructose aids tumour growth, but cancer cells usually lack the enzymes needed to metabolize this sugar. The liver converts dietary fructose to lipids that enter the blood, and cancer cells use the lipids to make membranes for proliferation.
When facing colorectal liver metastases or colorectal cancer that has spread to the liver, finding effective treatment options can be challenging. Dr. Katherine Poruk, a surgical oncologist at Mayo Clinic, says a specialized therapy known as hepatic artery infusion pump (HAIP) chemotherapy is an option for some. Watch: Dr. Katherine Poruk explains hepatic artery infusion […]
Liver swap gives two patients a second chance at life ROCHESTER, Minn. — Surgeons recently performed Mayo Clinic’s first paired living liver donation, a significant first step in helping more people with liver failure get a lifesaving transplant. “Liver transplantation is the only treatment option for most people with end-stage liver disease. But sadly, there […]
