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Skin can generate antibodies, independent of the rest of the immune system.Credit: kazuma seki/Getty The skin — once thought to be a mainly passive barrier — can produce its own antibodies that fight off infections, a pair of studies reports in Nature this week1,2. The findings could pave the way for the development of needle-free […]
Nature, Published online: 06 December 2024; doi:10.1038/s41586-024-08446-1 Publisher Correction: Spatially restricted immune and microbiota-driven adaptation of the gut
In an early-stage clinical trial, scientists used designer immune cells to “reboot” the immune systems of patients with various autoimmune diseases. The trial used a form of chimeric antigen receptor (CAR) T cell therapy, which has become a mainstay treatment for blood cancers, like leukemia. Only a few patients were included in this initial trial, […]
Phylogenetic tree based on the HVR of the VP2 gene, encoded by segment A. Credit: Virology (2024). DOI: 10.1016/j.virol.2024.110269 Researchers working to understand the prevalence of a virus that can severely damage the immune system of chickens have said that new strategies are needed to improve the control of the disease in the UK. Dr. […]
RESEARCH BRIEFINGS 06 November 2024 The body’s clock is essential for anticipating daily environmental changes. Surprisingly, clock genes are highly expressed in innate immune cells that produce the inflammatory protein interleukin-17A, particularly in body fat. The clock drives a rhythmic production of this protein, which in turn contributes to the metabolic rhythms of fat.
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