Researchers have voiced concerns after South Africa updated its health-research ethics guidelines to include a new section on heritable (or germline) human genome editing. Scientists say this could put the nation one step closer to accepting the controversial technique — which involves introducing genetic changes to sperm, eggs or embryos, such that the modifications will […]
Karczewski, K. J. et al. The mutational constraint spectrum quantified from variation in 141,456 humans. Nature 581, 434–443 (2020). ADS CAS PubMed Central Google Scholar Havrilla, J. M., Pedersen, B. S., Layer, R. M. & Quinlan, A. R. A map of constrained coding regions in the human genome. Nat. Genet. 51, 88–95 (2019). CAS Google […]
Scientists have assembled the most complete Tasmanian tiger genome to date from a century-old pickled head, providing a full DNA blueprint to potentially bring the extinct species back to life. The breakthrough — one of several new advances in Tasmanian tiger de-extinction efforts spearheaded by the company Colossal Biosciences — was made possible thanks to […]
Human remains from the Yayoi period, approximately 2,300 years ago, from which DNA was extracted. Credit: Kim et al 2024 A joint research group led by Jonghyun Kim and Jun Ohashi of the University of Tokyo has demonstrated that the majority of immigration to the Japanese Archipelago in the Yayoi and Kofun periods (between 3000 […]
