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Can robotic lab assistants speed up your work?

Researcher Yan Zeng looks over the machinery at the A-Lab, a fully automated laboratory at the Lawrence Berkeley National Laboratory in California.Credit: Marilyn Sargent/Berkeley Lab Stephan Noack’s official title is bioprocess engineer. In simple terms, he is a problem-solver. His colleagues at the Jülich Research Centre in Germany knock on his office door armed with […]

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candidate obesity drug boosts energy use and curbs calorie intake

Nogueiras, R., Nauck, M. A. & Tschöp, M. H. Nature Metab. 5933–944 (2023). Article PubMed Google Scholar Christoffersen, B. Ø. et al. Obesity 30841–857 (2022). Article PubMed Google Scholar Sass, F. et al. Nature https://doi.org/10.1038/s41586-024-08207-0 (2024). Article Google Scholar Wilding, J. P. H. et al. N. Engl. J. Med. 384989–1002 (2021). Article PubMed Google Scholar […]

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AI protein-prediction tool AlphaFold3 is now open source

AlphaFold3 can predict the structures of proteins as they interact with DNA.Credit: Werel et al./American Society for MicrobiologyMol*, RCSB PDB AlphaFold3 is open at last. Six months after Google DeepMind controversially withheld code from a paper describing the protein-structure prediction model, scientists can now download the software code and use the artificial intelligence (AI) tool […]

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Chemists make ‘impossible’ molecules that break 100-year-old bonding rule

Organic molecules, which contain carbon (pictured), form certain shapes because of how their atoms bond.Credit: Dennis Kunkel Microscopy/Science Photo Library For the first time, chemists have made a class of molecules previously thought too unstable to exist, and used them to generate exotic compounds1. Scientists say these notorious molecules, known as anti-Bredt olefins (ABOs), offer […]

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‘Smart’ insulin prevents diabetic highs — and deadly lows

Crystals of insulin. A new kind of insulin can modify its activity in response to glucose levels in the blood.Credit: Antonio Romero/Science Photo Library Scientists have designed a new form of insulin that can automatically switch itself on and off depending on glucose levels in the blood. In animals, this ‘smart’ insulin1 reduced high blood-sugar […]