Krabbe disease is a rare, inherited neurological disease that most commonly affects infants, but can also present later in life, including during adolescence and very rarely in adulthood, according to the NIH’s National Institute of Neurological Disorders and Stroke. Current clinical laboratory testing identifies individuals with Krabbe disease, but it is challenging to provide a […]
State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China Fuchu He, Cheng Chang, Ying Jiang, Yang Li, Aihua Sun, Liujun Tang, Chanjuan Wang, Xiaowen Wang, Yan Wang, Linhai Xie, Xiao Yang, Lingqiang Zhang, Yunping Zhu, Chenxi Jia, Chaoying Li, Dong Li, Yanchang Li, Zhongyang Liu, Jian Wang, Ping Xu, Wantao Ying & Xiaobo Yu International Academy of Phronesis Medicine (Guangdong), Guangdong, China Fuchu He, Yuezhong […]
Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland Aoxing Liu, Matti Pirinen, Zhiyu Yang, Mervi Aavikko, Timo P. Sipilä, Awaisa Ghazal, Aarno Palotie, Hanna M. Ollila, Taru Tukiainen, Mark J. Daly & Andrea Ganna Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA Aoxing Liu, Aarno Palotie, Mark J. Daly & Andrea Ganna Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA Aoxing […]
Spaceflight accelerates the symptoms of aging in astronaut bodies by inducing genomic instability, mitochondrial dysfunction, and increased inflammation. This is the first study to comprehensively examine biomarkers and pathways associated with spaceflight and terrestrial aging, frailty, and sarcopenia. Main Findings: Spaceflight induced notable changes in gene expression patterns related to frailty and muscle loss indicative […]
