Researchers discover an aging and inflammation biomarker

Mayo Clinic researchers found that the gene expression of Il23r (depicted in red), which increases in aged blood at the protein level, is present in aged kidney and is associated with the senescence marker p16 (shown in green). When IL-23R signaling is overactive, it can lead to inflammation and tissue damage. Mayo Clinic researchers found that IL-23R increases with age and decreases in response to drugs that attack senescent cells. The bloodstream is teeming with…